MFSD2B 抗体 (Center)
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Quick Overview for MFSD2B 抗体 (Center) (ABIN783765)
抗原
适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects MFSD2B at Center.
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交叉反应 (详细)
- Species reactivity (tested):Human, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the center of human MFSD2B
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- MFSD2B (Major Facilitator Superfamily Domain Containing 2B (MFSD2B))
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别名
- MFSD2B
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背景
- Multidrug transporters, such as MFSD2B, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2B is closely related to MFSD2A, which is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting, playing a major role in the induction of MFSD2A expression during adaptive thermogenesis. Unlike MFSD2A, MFSD2B is expressed in few tissues and at relatively low levels, and is not induced during fasting, suggesting that MFSD2B may play other roles.
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基因ID
- 388931
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NCBI登录号
- NP_001073942
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UniProt
- A6NFX1
抗原
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