PAPPA2 抗体 (N-Term)
Quick Overview for PAPPA2 抗体 (N-Term) (ABIN783757)
抗原
See all PAPPA2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Pappalysin-2 / PAPPA2 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the amino terminus of human PLAC3
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anti-Pappalysin 2 (PAPPA2) (AA 888-1093) antibody
PAPPA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pappalysin 2 (PAPPA2) (AA 1309-1492) antibodyPAPPA2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Pappalysin 2 (PAPPA2) (AA 108-157) antibodyPAPPA2 适用: 人, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Pappalysin 2 (PAPPA2) (AA 432-481) antibodyPAPPA2 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- PAPPA2 (Pappalysin 2 (PAPPA2))
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别名
- Pappalysin-2 / PAPPA2
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背景
- PLAC3 (placenta-specific protein 3), also known as PAPP-A2, is a metalloproteinase that cleaves the insulin-like growth factor-binding protein (IGFBP)-5 in a IGF-independent fashion. It has been suggested that the cleavage of IGFBP-5 and to a lesser extent IGFBP-3 produced in the maternal decidua promotes feto-placental growth. Recent studies have shown elevated levels of PLAC3 in hypertensive disorders of pregnancy including preeclampsia and HELLP (hemolysis, elevated liver enzymes, and low platelets) syndrome.Synonyms: PAPP-A2, PAPP-E, PLAC3, Pregnancy-associated plasma protein A2, Pregnancy-associated plasma protein E1
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基因ID
- 60676
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NCBI登录号
- NP_064714
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UniProt
- Q9BXP8
抗原
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