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KPNA4 抗体 (N-Term)

KPNA4 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783731
发货至: 中国
  • 抗原 See all KPNA4 抗体
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    抗原表位
    • 15
    • 7
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 41
    • 36
    • 14
    • 5
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 50
    • 1
    • 1
    克隆类型
    • 51
    • 1
    多克隆
    标记
    • 22
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNA4 antibody is un-conjugated
    应用范围
    • 39
    • 20
    • 14
    • 13
    • 11
    • 9
    • 7
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects KPNA4 / Importin alpha-4 at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid peptide near the amino terminus of human KPNA4
    Top Product
    Discover our top product KPNA4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原
    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))
    别名
    KPNA4 / Importin alpha-4 (KPNA4 产品)
    别名
    IPOA3 antibody, QIP1 antibody, SRP3 antibody, 6 antibody, ATIMPALPHA3 antibody, IMPA-3 antibody, IMPORTIN ALPHA 3 antibody, IMPORTIN ALPHA ISOFORM 3 antibody, MODIFIER OF SNC1 antibody, T10M13.16 antibody, T10M13_16 antibody, LOC100224013 antibody, 1110058D08Rik antibody, importin antibody, ipoa3 antibody, qip1 antibody, srp3 antibody, impa3 antibody, wu:fa56d07 antibody, wu:fa66g10 antibody, wu:fe14c04 antibody, wu:fi04h11 antibody, wu:fi19b05 antibody, karyopherin subunit alpha 4 antibody, ARM repeat superfamily protein antibody, importin alpha 3 antibody, karyopherin (importin) alpha 4 antibody, karyopherin alpha 4 (importin alpha 3) S homeolog antibody, karyopherin alpha 4 (importin alpha 3) antibody, KPNA4 antibody, MOS6 antibody, LOC100533341 antibody, Kpna4 antibody, kpna4.S antibody, kpna4 antibody
    背景
    Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-alpha-induced nuclear import of NF-kappaB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.Synonyms: Importin alpha Q1, Karyopherin subunit alpha-4, QIP1
    基因ID
    3840
    NCBI登录号
    NP_002259
    UniProt
    O00629
    途径
    Protein targeting to Nucleus
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