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KPNA4 抗体 (N-Term)

This anti-KPNA4 antibody is a 兔 多克隆 antibody detecting KPNA4 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783731
发货至: 中国

Quick Overview for KPNA4 抗体 (N-Term) (ABIN783731)

抗原

See all KPNA4 抗体
KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

适用

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人, 小鼠, 大鼠

宿主

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  • 1
  • 1

克隆类型

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  • 1
多克隆

标记

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This KPNA4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 7
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    • 5
    • 4
    • 3
    • 1
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    N-Term

    特异性

    This antibody detects KPNA4 / Importin alpha-4 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    15 amino acid peptide near the amino terminus of human KPNA4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    KPNA4 (Karyopherin (Importin) alpha 4 (KPNA4))

    别名

    KPNA4 / Importin alpha-4

    背景

    Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. Molecules containing the classical nuclear localization signal (NLS) are transported into the nucleus by alpha/beta heterodimers. KPNA3 has been shown to be important in the TNF-alpha-induced nuclear import of NF-kappaB. It is also involved in the stress-mediated nuclear stabilization of p53 and the nuclear import and replication of HIV-1 in both dividing and non-dividing cells.Synonyms: Importin alpha Q1, Karyopherin subunit alpha-4, QIP1

    基因ID

    3840

    NCBI登录号

    NP_002259

    UniProt

    O00629

    途径

    Protein targeting to Nucleus
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