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KPNA1 抗体 (N-Term)

The 兔 多克隆 anti-KPNA1 antibody (ABIN783729) specifically detects KPNA1 in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN783729
发货至: 中国
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Quick Overview for KPNA1 抗体 (N-Term) (ABIN783729)

抗原

See all KPNA1 抗体
KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

适用

  • 38
  • 18
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  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
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  • 1
人, 小鼠, 大鼠

宿主

  • 28
  • 9
  • 1

克隆类型

  • 32
  • 6
多克隆

标记

  • 27
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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This KPNA1 antibody is un-conjugated

应用范围

  • 26
  • 15
  • 8
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  • 3
  • 2
  • 2
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody detects KPNA1 / Importin alpha-1 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    15 amino acid peptide near the amino terminus of human KPNA1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    KPNA1 (Karyopherin alpha 1 (Importin alpha 5) (KPNA1))

    别名

    KPNA1 / Importin alpha-1

    背景

    Karyopherin, a cytosolic and heterodimeric protein complex consisting of alpha and beta subunits, is responsible for targeting proteins with nuclear localization signals to the nuclear pore complex by an energy requiring, Ran-dependent mechanism. The alpha subunit and imported substrate enter the nucleus and accumulate in the nucleoplasm, while the beta subunit accumulates at the NPC. KPNA1, also known as importin alpha 5, is the alpha subunit of karyopherin, which forms a complex with importin subunit beta-1 and functions in nuclear protein import as an adapter protein for nuclear receptor KPNB1. It is ubiquitously expressed and polyubiquitinated in the presence of RAG1. KPNA1 interacts with various virus nucleoproteins, including those of Ebola and influenza.Synonyms: IPOA5, Karyopherin alpha 1, NPI-1, Nucleoprotein interactor 1, RAG cohort protein 2, RCH2, SRP1, SRP1-beta

    基因ID

    3836

    NCBI登录号

    NP_002255

    UniProt

    P52294

    途径

    M Phase, Protein targeting to Nucleus
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