BANP 抗体 (Center)
Quick Overview for BANP 抗体 (Center) (ABIN783725)
抗原
See all BANP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects BANP / SMAR1 at Center.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 14 amino acid peptide near the center of human BANP
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anti-Protein BANP (BANP) (AA 1-260) antibody
BANP 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Protein BANP (BANP) (AA 1-469) antibodyBANP 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Protein BANP (BANP) (AA 30-390) antibodyBANP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 1524CT337-6-32 unconjugated
anti-Protein BANP (BANP) antibodyBANP 适用: 人 WB, IHC (p) 宿主: 小鼠 Monoclonal 4C2 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- Antibody is supplied in PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- BANP (Protein BANP (BANP))
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别名
- BANP / SMAR1
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背景
- BANP was initially identified as a binding protein to BTG3 in a yeast two-hybrid screen. BANP acts as a tumor suppressor by stabilizing p53 expression and leading to cell cycle arrest. p53 in turn binds to upstream elements of the BANP promoter, thereby forming a feedback loop. BANP is down-regulated in advanced stages of human breast cancer, and its overexpression in breast cancer cell lines inhibits their ability to metastasize by modulating TGF-b signaling. Furthermore, BANP can modulate NF-kB transactivation and can inhibit tumorigenesis by regulating NF-kB target genes. Recent experiments have shown that BANP can also repress HIV-1 LTR mediated transcription by tethering the LTR matrix attachment region to nuclear matrix.Synonyms: BEN domain-containing protein 1, BEND1, Btg3-associated nuclear protein, Scaffold/matrix-associated region-1-binding protein
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基因ID
- 54971
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NCBI登录号
- NP_001167010
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UniProt
- Q8N9N5
抗原
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