NLRP10 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for NLRP10 抗体 (N-Term) (ABIN783715)
抗原
See all NLRP10 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody detects NALP10 at N-term.
-
交叉反应 （详细）
- Species reactivity (tested):Human
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 14 amino acid peptide near the amino terminus of human NALP10
-
-
anti-NLR Family, Pyrin Domain Containing 10 (NLRP10) (AA 589-655) antibody
NLRP10 适用: 人 ELISA, WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 10 (NLRP10) (N-Term) antibodyVerified NLRP10 适用: 小鼠 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 10 (NLRP10) antibodyNLRP10 适用: 人, 小鼠 ELISA, WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 10 (NLRP10) (AA 1-300) antibodyNLRP10 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 10 (NLRP10) (AA 493-509) antibodyNLRP10 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 10 (NLRP10) (AA 466-494) antibodyNLRP10 适用: 人 ELISA, WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
-
-
- NLRP10 (NLR Family, Pyrin Domain Containing 10 (NLRP10))
-
别名
- NLRP10
-
背景
- NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP10 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It was initially identified as PYNOD, an Apaf-1-like protein that binds to ASC, caspase-1 and IL-1b, inhibiting the autoprocessing of caspase-1, caspase-1-mediated IL-1b processing, and ASC aggregation. NALP10 is thus a potent regulator of apoptosis and inflammation.Synonyms: NACHT LRR and PYD domains-containing protein 10, NALP10, NOD8, Nucleotide-binding oligomerization domain protein 8, PYNOD
-
基因ID
- 338322
-
NCBI登录号
- NP_789791
-
UniProt
- Q86W26
-
途径
- Inflammasome
抗原
-
