NALP8 抗体 (N-Term)
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Quick Overview for NALP8 抗体 (N-Term) (ABIN783713)
抗原
See all NALP8 (NLRP8) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects NALP8 at N-term. This antibody is predicted to not cross-react with other NALP family members.
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交叉反应 (详细)
- Species reactivity (tested):Human.
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纯化方法
- Affinity Chromatography purified via peptide column
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免疫原
- 16 amino acid peptide near the amino terminus of Human NALP8
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % Sodium Azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- NALP8 (NLRP8) (NLR Family, Pyrin Domain Containing 8 (NLRP8))
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别名
- NALP8
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背景
- NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP8 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It maps to chromosome 19q13.42 and is thought to be expressed in testis and ovary, suggesting that NALP8 may be involved in reproduction. Surprisingly, NALP8 seems to be universal in mammals except for rodents, suggesting that the gene may have been lost during evolution.Synonyms: LRR and PYD domains-containing protein 8, NACHT, NLRP8, NOD16, PAN4, PYRIN and NACHT-containing protein 4
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基因ID
- 126205
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NCBI登录号
- NP_789781
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UniProt
- Q86W28
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途径
- Inflammasome
抗原
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