NLRP7 抗体 (N-Term)
This 兔 多克隆 anti-NLRP7 antibody specifically detects NLRP7 in WB 和 EIA. The antibody is reactive with 人 samples.
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产品编号 ABIN783711
发货至:
中国
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Quick Overview for NLRP7 抗体 (N-Term) (ABIN783711)
抗原
See all NLRP7 抗体
NLRP7
(NLR Family, Pyrin Domain Containing 7 (NLRP7))
适用
人
宿主
兔
克隆类型
多克隆
标记
This NLRP7 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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特异性
- This antibody detects NLRP7 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the amino terminus of human NALP7
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anti-NLR Family, Pyrin Domain Containing 7 (NLRP7) (AA 89-187) antibody
NLRP7 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))
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别名
- NLRP7
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背景
- NOD proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins. NALP7, also known as PYPAF3, a member of the related PYRIN-containing APAF1-like proteins (PYPAFs/NALPs) is thought to play a crucial role in cell proliferation. NALP7 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. It is expressed in numerous tissues including uterus and ovary, with low levels in heart and brain. NALP7 inhibits caspase-1-dependent interleukin-1beta secretion and is a feedback regulator of interleukin-1beta secretion. Defects in the NALP7 gene are known to cause the formation of a hydatidiform mole (HYDM) and reduce the growth of carcinoma cell lines.Synonyms: LRR and PYD domains-containing protein 7, NALP7, NOD12, Nucleotide-binding oligomerization domain protein 12, PYPAF3, PYRIN-containing APAF1-like protein 3
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基因ID
- 199713
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NCBI登录号
- NP_001120727
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UniProt
- Q8WX94
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途径
- Inflammasome
抗原
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