NLRP5 抗体 (C-Term)
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Quick Overview for NLRP5 抗体 (C-Term) (ABIN783707)
抗原
See all NLRP5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects NLRP5 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 14 amino acid peptide near the carboxy terminus of human NALP5
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anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (AA 157-256) antibody
NLRP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (C-Term) antibodyVerified NLRP5 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (AA 121-170) antibodyNLRP5 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (N-Term) antibodyNLRP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, Pyrin Domain Containing 5 (NLRP5) (N-Term) antibodyNLRP5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- NLRP5 (NLR Family, Pyrin Domain Containing 5 (NLRP5))
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别名
- NLRP5
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背景
- NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP5, also known as MATER, is a maternal gene required for early embryonic development in mice. Increased NALP5 expression was observed in two neuronal injury models, and transient expression of recombinant NALP5 in neurons induced caspase-3 activation and apoptosis, suggesting that NALP5 also plays a role in caspase activation and apoptosis in injured neurons, and may thus represent a novel target for therapeutic treatment in neurodegenerative disorders.Synonyms: LRR and PYD domains-containing protein 5, MATER, NALP5
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基因ID
- 126206
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NCBI登录号
- NP_703148
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UniProt
- P59047
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途径
- Inflammasome
抗原
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