NLRC3 抗体 (Center)
This anti-NLRC3 antibody is a 兔 多克隆 antibody detecting NLRC3 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for NLRC3 抗体 (Center) (ABIN783697)
抗原
See all NLRC3 抗体
NLRC3
(NLR Family, CARD Domain Containing 3 (NLRC3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This NLRC3 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- Center
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特异性
- This antibody detects NOD3 at Center.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the center of human NOD3
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anti-NLR Family, CARD Domain Containing 3 (NLRC3) (Internal Region) antibody
NLRC3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- NLRC3 (NLR Family, CARD Domain Containing 3 (NLRC3))
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别名
- NOD3
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背景
- NOD3 is a member of the NOD (nucleotide-binding oligomerization domain) family, a group of proteins that are involved in innate immune defense. NOD3 also known as NLR family CARD containing 3 (NLRC3), is predominantly expressed in the immune system, particularly in T lymphocytes, and its expression is strongly down-regulated following stimulation of the T-cell receptor complex and CD28, suggesting that NOD3 plays a role in attenuating the activation of T cells. NOD3 inhibits NF-?B, AP-1 and NFAT transcriptional activation in Jurkat T cells downstream of CD3/CD28 stimulation or treatment with PMA/ionomycin and decreases IL-2 and CD25 mRNA induction in activated cells.Synonyms: CLR16.2, FLJ00348, NLRC3, NOD3
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基因ID
- 197358
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NCBI登录号
- NP_849172
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UniProt
- Q7RTR2
抗原
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