TRIM71 抗体 (C-Term)
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Quick Overview for TRIM71 抗体 (C-Term) (ABIN783687)
抗原
See all TRIM71 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects TRIM71 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the carboxy terminus of human TRIM71
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anti-Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) (AA 125-209) antibody
TRIM71 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) (AA 390-402) antibodyVerified TRIM71 适用: 人, 小鼠 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71) (C-Term) antibodyTRIM71 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, 斑马鱼, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- TRIM71 (Tripartite Motif Containing 71, E3 Ubiquitin Protein Ligase (TRIM71))
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别名
- TRIM71
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背景
- TRIM71 is the mammalian ortholog to the C. elegans heterochronic protein Lin41, a protein that is thought to be important in postembryonic development , and is genetically and biochemically downstream of both Shh and Fgf signaling pathways. Similar to its C. elegans homolog, TRIM71 is a target of the microRNA let-7 and is likely to play a role in mammalian development. Recent experiments have indicated that TRIM71 is an E3 ubiquitin ligase and can interact with the Dicer and the Argonaute proteins Ago1, Ago2, and Ago4. Overexpression and depletion of TRIM71 led to inverse changes in Ago2 protein levels, suggesting TRIM71 can regulate Ago2 turnover. Finally, TRIM71 cooperates with the pluripotency factor Lin-28 in regulating let-7.Synonyms: LIN41, Protein lin-41 homolog, Tripartite motif-containing protein 71
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基因ID
- 131405
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NCBI登录号
- NP_001034200
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UniProt
- Q2Q1W2
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途径
- Tube Formation
抗原
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