CRISP2 抗体 (N-Term)
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Quick Overview for CRISP2 抗体 (N-Term) (ABIN783679)
抗原
See all CRISP2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects CRISP2 at N-term.
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the amino terminus of human CRISP2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CRISP2 (Cysteine-Rich Secretory Protein 2 (CRISP2))
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别名
- CRISP2
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背景
- The cysteine-rich secretory proteins (CRISP) family is a group of four proteins that are strongly expressed in the male reproductive tract and have been implicated in having roles in male fertility. CRISP2, also known as TPX1, has been implicated in the adhesion between spermatids and Sertoli cells, and with CRISP1, is thought to be involved in sperm-egg fusion. CRISP2 has been shown to regulate the Ca2+ influx through ryanodine receptors (RYR) and may influence the acrosome reaction or sperm motility. CRISP2 has also been shown to bind to the mitogen-activated protein kinase kinase kinase 11 (MAP3K11) and localizes to the developing acrosome, suggesting this CRISP2-MAP3K11 complex may have a role in acrosome development.Synonyms: CRISP-2, CT36, Cancer/testis antigen 36, Cysteine-rich secretory protein 2, GAPDL5, TPX1, Testis-specific protein TPX-1
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基因ID
- 7180
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NCBI登录号
- NP_001135879
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UniProt
- P16562
抗原
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