SCUBE1 抗体 (Center)
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Quick Overview for SCUBE1 抗体 (Center) (ABIN783649)
抗原
See all SCUBE1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应 (详细)
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 14 amino acid peptide near the center of human SCUBE1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- 14 amino acid peptide near the center of human SCUBE1
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- SCUBE1 (Signal Peptide, CUB Domain, EGF-Like 1 (SCUBE1))
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别名
- SCUBE1
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背景
- SCUBE1 is an EGF-related protein with a CUB (C1s-like) domain that is expressed primarily in the developing gonad, nervous system, somites, surface ectoderm and limb buds. The N-terminal EGF-like repeats of SCUBE1 participate in the formation of adhesions in a Ca2+-dependent fashion. In contrast, the C-terminal cysteine-rich motifs and CUB domain can directly bind and antagonize bone morphogenic protein activity, genetic ablation of this region resulted in brain malformation in mice embryos, suggesting SCUBE1 plays a role in brain morphogenesis. SCUBE1 has also been implicated in early craniofacial development in mice.Synonyms: Signal peptide CUB and EGF-like domain-containing protein 1
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基因ID
- 80274
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NCBI登录号
- NP_766638
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UniProt
- Q8IWY4
抗原
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