TCTN1 抗体 (N-Term)
This anti-TCTN1 antibody is a 兔 多克隆 antibody detecting TCTN1 in WB, IF 和 EIA. Suitable for 人 和 小鼠.
Quick Overview for TCTN1 抗体 (N-Term) (ABIN783637)
抗原
See all TCTN1 抗体
TCTN1
(Tectonic Family Member 1 (TCTN1))
适用
人, 小鼠
宿主
兔
克隆类型
多克隆
标记
This TCTN1 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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特异性
- This antibody detects TCTN1 . It is predicted to not cross-react with other TCTN members. Multiple isoforms are known to exist, this antibody recognizes isoforms 1 - 3.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the amino terminus of human TCTN1
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anti-Tectonic Family Member 1 (TCTN1) (N-Term) antibody
TCTN1 适用: 大鼠, 人, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tectonic Family Member 1 (TCTN1) (AA 130-310) antibodyTCTN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- TCTN1 (Tectonic Family Member 1 (TCTN1))
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别名
- Tectonic-1
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背景
- TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.Synonyms: TCTN1, TECT1
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基因ID
- 79600
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NCBI登录号
- NP_001076006
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UniProt
- Q2MV58
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途径
- Tube Formation
抗原
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