SIP1 抗体 (C-Term)
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Quick Overview for SIP1 抗体 (C-Term) (ABIN783630)
抗原
See all SIP1 (GEMIN2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid peptide near the carboxy terminus of human SIP1
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anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) antibody
KD Validated GEMIN2 适用: 人 WB, ICC, FACS 宿主: 兔 Monoclonal 23GB5835 unconjugated Recombinant Antibody
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (C-Term) antibodyGEMIN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) antibodyGEMIN2 适用: 人 WB, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) antibodyGEMIN2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 1-280) antibodyGEMIN2 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 12-280) antibodyGEMIN2 适用: 人, 小鼠, 非洲爪蟾 WB, ELISA, IF, IP, ICC, FACS 宿主: 小鼠 Monoclonal 2E17 unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (AA 51-150) antibodyGEMIN2 适用: 大鼠 WB, ELISA, IF (p), IHC (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (Middle Region) antibodyGEMIN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 兔, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (N-Term) antibodyGEMIN2 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2) (N-Term) antibodyGEMIN2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- SIP1 (GEMIN2) (Gem (Nuclear Organelle) Associated Protein 2 (GEMIN2))
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别名
- SIP1 / GEMIN2
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背景
- SIP1 is one of the proteins found in the SMN complex, which consists of the survival of motor neuron (SMN) protein and several gemin proteins. The SMN complex is localized to a subnuclear compartment called gems (gemini of coiled bodies) and is required for assembly of spliceosomal snRNPs and for pre-mRNA splicing. SIP1 interacts directly with the SMN and it is required for formation of the SMN complex. A knockout mouse targeting the mouse homolog of this gene exhibited disrupted snRNP assembly and motor neuron degeneration. However, knockdown of the SIP1 mRNA in motor neurons showed normal motor axons while that of SMN mRNA did show abnormal motor axon outgrowth, indicating that SIP1 may have additional roles outside of the SMN complex.Synonyms: Component of gems 2, GEMIN-2, SMN-interacting protein 1, Survival of motor neuron protein-interacting protein 1
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基因ID
- 8487
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NCBI登录号
- NP_001009182
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UniProt
- O14893
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途径
- Ribonucleoprotein Complex Subunit Organization, Tube Formation
抗原
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