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SIRT3 抗体 (Center)

This anti-SIRT3 antibody is a 小鸡 多克隆 antibody detecting SIRT3 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783622
发货至: 中国

Quick Overview for SIRT3 抗体 (Center) (ABIN783622)

抗原

See all SIRT3 抗体
SIRT3 (Sirtuin 3 (SIRT3))

适用

  • 95
  • 43
  • 21
  • 9
  • 5
  • 5
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 85
  • 23
  • 2
  • 2
  • 1
小鸡

克隆类型

  • 90
  • 24
多克隆

标记

  • 71
  • 15
  • 11
  • 4
  • 4
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This SIRT3 antibody is un-conjugated

应用范围

  • 101
  • 55
  • 52
  • 21
  • 20
  • 11
  • 9
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 12
    • 10
    • 8
    • 8
    • 8
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Center

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    17 amino acid peptide near the center of human SIRT3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    SIRT3 (Sirtuin 3 (SIRT3))

    别名

    SIRT3

    背景

    The Silent Information Regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and have important functions in the regulation of metabolism, growth and differentiation, inflammation, cellular survival, as well as in senescence, lifespan extension and several age-related diseases. Sirtuins are NAD+-dependent histone/protein deacetylases (HDAC) and SIRT3 is the only sirtuin whose increased expression has been shown to correlate with an extended life span in humans. It is localized in the mitochondrial matrix, where it regulates the acetylation levels of metabolic enzymes, including acetyl coenzyme A synthetase 2. SIRT3 is stress-responsive and its increased expression protects myocytes from genotoxic and oxidative stress-mediated cell death.Synonyms: NAD-dependent deacetylase sirtuin-3 mitochondrial, SIR2-like protein 3, SIR2L3, SIRT-3, hSIRT3, sirtuin (silent mating type information regulation 2 homolog) 3 (S. cerevisiae), sirtuin 3, sirtuin type 3, sirtuin-3

    基因ID

    23410

    NCBI登录号

    NP_001017524

    UniProt

    Q9NTG7
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