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ANAPC10 抗体 (Center)

The 兔 多克隆 anti-ANAPC10 antibody (ABIN783594) specifically detects ANAPC10 in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN783594
发货至: 中国
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Quick Overview for ANAPC10 抗体 (Center) (ABIN783594)

抗原

See all ANAPC10 抗体
ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

适用

  • 24
  • 19
  • 5
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
人, 小鼠, 大鼠

宿主

  • 35
  • 4

克隆类型

  • 36
  • 2
多克隆

标记

  • 18
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
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This ANAPC10 antibody is un-conjugated

应用范围

  • 29
  • 13
  • 13
  • 10
  • 5
  • 5
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
    • 8
    • 4
    • 1
    • 1
    • 1
    Center

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid peptide near the center of human APC10
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    ANAPC10 (Anaphase Promoting Complex Subunit 10 (ANAPC10))

    别名

    APC10 / ANAPC10

    背景

    Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC10 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. It has been suggested that APC10 plays a role to regulate the binding of specific substrates to the APC/C complex, similar to that of coactivators.Synonyms: Anaphase-promoting complex subunit 10, Cyclosome subunit 10

    基因ID

    10393

    NCBI登录号

    NP_055700

    UniProt

    Q9UM13

    途径

    M Phase
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