VPS53 抗体 (C-Term)
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Quick Overview for VPS53 抗体 (C-Term) (ABIN783564)
抗原
See all VPS53 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects VPS53 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide from near the carboxy terminus of human VPS53
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anti-Vacuolar Protein Sorting 53 Homolog (VPS53) (AA 111-140), (N-Term) antibody
VPS53 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20279 unconjugated
anti-Vacuolar Protein Sorting 53 Homolog (VPS53) antibodyVPS53 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 53 Homolog (VPS53) (AA 1-670) antibodyVPS53 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 53 Homolog (VPS53) (AA 431-480) antibodyVPS53 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 兔, Hamster WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 53 Homolog (VPS53) (Middle Region) antibodyVPS53 适用: 人, 小鼠, 大鼠, 斑马鱼, Cow, 马, 兔, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Vacuolar Protein Sorting 53 Homolog (VPS53) (N-Term) antibodyVPS53 适用: 人, 小鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- VPS53 (Vacuolar Protein Sorting 53 Homolog (VPS53))
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别名
- VPS53
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背景
- The sorting of acid hydrolases to lysosomes rely on mannose 6-phosphate receptors that cycle between the trans-Golgi network (TGN) and endosomes. The maintenance of this cycle requires the function of the mammalian Golgi-associated retrograde protein (GARP) complex which is composed of three subunits: VPS52, VPS53, and VPS54. Depletion of any of these three proteins, such as by RNAi, impairs the retrograde transport of multiple TGN proteins. VPS53 was identified as an HIV dependency factor (HDF) and plays a role in viral entry to the cell, suggesting that VPS53 may be an important drug target in HIV treatment. At least five isoforms of VPS53 are known to exist.Synonyms: PP13624, Vacuolar protein sorting-associated protein 53 homolog
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基因ID
- 55275
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NCBI登录号
- NP_001121631
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UniProt
- Q5VIR6
抗原
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