SP110 抗体 (N-Term)
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北京 101111
Quick Overview for SP110 抗体 (N-Term) (ABIN783560)
抗原
See all SP110 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects SP110 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid peptide near the amino terminus of the human IPR1
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anti-SP110 Nuclear Body Protein (SP110) (AA 271-380) antibody
SP110 适用: 人 WB, ELISA, IHC (p), IP, RNAi 宿主: 小鼠 Monoclonal 8C8 unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 271-380) antibodySP110 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 6F11 unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 1-547) antibodySP110 适用: 人 WB, IF, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 137-386) antibodySP110 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 1-547) antibodySP110 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 1-290) antibodySP110 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 271-380) antibodySP110 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (AA 612-661) antibodySP110 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (C-Term) antibodySP110 适用: 人, 犬, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-SP110 Nuclear Body Protein (SP110) (C-Term) antibodySP110 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- SP110 (SP110 Nuclear Body Protein (SP110))
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别名
- SP110
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背景
- Susceptibility to tuberculosis (TB) in mice has recently been attributed to the IPR1 gene. IPR1 is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified. SP110 is the closest homolog of the IPR1 protein in humans. The IPR1/Sp110 gene product might play a role in integrating signals generated by intracellular pathogens with mechanisms controlling innate immunity, cell death, and pathogenesis. IPR1/Sp110 is up-regulated after infection with M. tuberculosis and required by Anaplasma phagocytophilum for infection of human promyelocytic cells. Defects in Sp110 are a cause of severely impaired resistance to infection by M. tuberculosis.Synonyms: FLJ22835, IPR1, SP-110, SP110 nuclear body protein, Speckled 110 kD, VODI
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基因ID
- 3431
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NCBI登录号
- NP_001171944
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UniProt
- Q9HB58
抗原
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