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MORF4 抗体 (N-Term)

This 兔 多克隆 anti-MORF4 antibody specifically detects MORF4 in WB, IF, IHC (p) 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN783556
发货至: 中国
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Quick Overview for MORF4 抗体 (N-Term) (ABIN783556)

抗原

See all MORF4 抗体
MORF4 (Mortality Factor 4 (MORF4))

适用

  • 6
  • 3
  • 3
  • 2
  • 1
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人, 小鼠, 大鼠

宿主

  • 4
  • 2

克隆类型

  • 4
  • 2
多克隆

标记

  • 6
This MORF4 antibody is un-conjugated

应用范围

  • 6
  • 3
  • 1
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  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    18 amino acid peptide from near the amino terminus of human MORF4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    MORF4 (Mortality Factor 4 (MORF4))

    别名

    MORF4

    背景

    Cellular senescence is the terminal non-dividing state that normal cells enter following completion of their proliferative potential. Fusions of immortal human cell lines with each other have led to their assignment to one of four complementation groups. Mortality factor 4 (MORF4) was identified as the lead member of a family of transcription factor-like proteins that reverses this immortal phenotype. Like other members in this family, MORF4 is localized to the nucleus and possesses transcription factor-like motifs such as helix-loop-helix and a leucine zipper motif that might allow it to form transcriptionally active homo- or heterodimers. MORF4 has been shown to bind to the transcription corepressors mSin3A and TLE, suggesting that together, these complexes may play a role in transcriptional repression of genes that lead to cellular senescence.Synonyms: CSR, CSRB, SEN, SEN1, mortality factor 4

    UniProt

    Q9Y690
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