STEAP4 抗体 (Center)
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Quick Overview for STEAP4 抗体 (Center) (ABIN783554)
抗原
See all STEAP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects STEAP4 at Center.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 14 amino acid peptide from near the center of human STEAP4
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- STEAP4 (STEAP Family Member 4 (STEAP4))
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别名
- STEAP4
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背景
- The six-transmembrane epithelial antigen of prostate 4 (STEAP4) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP3), STEAP4 promotes both iron and copper reduction. STEAP4 is highly expressed in placenta, lung, heart and prostate tissues, and overexpressed in prostate cancer cells compared to normal prostate cells. Overexpression of STEAP4 in prostate cells significantly increases cell growth and colony formation, suggesting STEAP4 may have a role in cell proliferation and prostate cancer progression. At least two isoforms are known to exist for this protein. This STEAP4 antibody does not cross-react with other STEAP proteins.Synonyms: Metalloreductase STEAP4, STAMP2, STEAP-4, Six-transmembrane epithelial antigen of prostate 4, SixTransMembrane protein of prostate 2, TNFAIP9, Tumor necrosis factor, alpha-induced protein 9
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基因ID
- 79689
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NCBI登录号
- NP_078912
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UniProt
- Q687X5
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途径
- Transition Metal Ion Homeostasis
抗原
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