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NUP160 抗体 (C-Term)

This anti-NUP160 antibody is a 兔 多克隆 antibody detecting NUP160 in WB, IHC (p) 和 EIA. Suitable for 小鼠, 人 和 大鼠.
产品编号 ABIN783552
发货至: 中国

Quick Overview for NUP160 抗体 (C-Term) (ABIN783552)

抗原

See all NUP160 抗体
NUP160 (Nucleoporin 160kDa (NUP160))

适用

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小鼠, 人, 大鼠

宿主

  • 47

克隆类型

  • 47
多克隆

标记

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This NUP160 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    14 amino acid peptide from near the carboxy terminus of human NUP160
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    NUP160 (Nucleoporin 160kDa (NUP160))

    别名

    NUP160

    背景

    The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.Synonyms: 160 kDa nucleoporin, KIAA0197, NUP120, Nuclear pore complex protein Nup160, Nucleoporin Nup160

    基因ID

    23279

    NCBI登录号

    NP_056046

    UniProt

    Q12769

    途径

    Protein targeting to Nucleus
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