NUP160 抗体 (C-Term)
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Quick Overview for NUP160 抗体 (C-Term) (ABIN783552)
抗原
See all NUP160 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 14 amino acid peptide from near the carboxy terminus of human NUP160
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- NUP160 (Nucleoporin 160kDa (NUP160))
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别名
- NUP160
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背景
- The nuclear pore complex (NPC) is a protein assembly localized at the nuclear rim and mediates macromolecular transport between the nucleus and the cytoplasm. The mammalian nucleoporin (NUP)-160 is part of the hetero-oligomeric complex that also contains NUP107, NUP133, NUP96, and mammalian homolog of yeast sec13p. While the majority of the NUP107-160 nuclear pore sub-complex localizes to the nuclear pore, a small fraction is observed at kinetochores and pro-metaphase spindle poles in mitotic cells in association with proteins such as Mad1, Mad2, Bub3 and Cdc20. Immunodepletion of the NUP107-160 complex resulted in defective spindle assembly indicating that it has multiple functions. NUP160 has recently been identified as an HIV dependency factor (HDF), suggesting that NUP160 may be an important drug target in HIV treatment. Multiple isoforms of NUP160 are known to exist.Synonyms: 160 kDa nucleoporin, KIAA0197, NUP120, Nuclear pore complex protein Nup160, Nucleoporin Nup160
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基因ID
- 23279
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NCBI登录号
- NP_056046
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UniProt
- Q12769
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途径
- Protein targeting to Nucleus
抗原
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