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FOXO4 抗体 (N-Term)

FOXO4 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN783544
发货至: 中国
  • 抗原 See all FOXO4 抗体
    FOXO4 (Forkhead Box O4 (FOXO4))
    抗原表位
    • 20
    • 18
    • 16
    • 10
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    N-Term
    适用
    • 138
    • 72
    • 64
    • 10
    • 6
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 136
    • 1
    • 1
    克隆类型
    • 127
    • 11
    多克隆
    标记
    • 66
    • 8
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    This FOXO4 antibody is un-conjugated
    应用范围
    • 107
    • 50
    • 39
    • 39
    • 24
    • 18
    • 17
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography purified via peptide column
    免疫原
    15 amino acid peptide near the amino terminus of human FOXO4
    Top Product
    Discover our top product FOXO4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    FOXO4 (Forkhead Box O4 (FOXO4))
    别名
    FOXO4 / AFX1 / MLLT7 (FOXO4 产品)
    别名
    FOXO4 antibody, foxo4 antibody, AFX antibody, AFX1 antibody, MLLT7 antibody, Afxh antibody, Mllt7 antibody, afx antibody, RGD1561201 antibody, forkhead box O4 antibody, forkhead box O4 L homeolog antibody, FOXO4 antibody, foxo4.L antibody, Foxo4 antibody
    背景
    FOXO4 is a ubiquitously expressed protein member of a subfamily of the forkhead homeotic gene family of transcription factors and shuttles between the cytoplasm and nucleus. FOXO transcription factors are key players of cell fate decisions, metabolism, stress resistance, tumor suppression and are regulated by growth factors, oxidative stress or nutrient deprivation. In the absence of PI3K/AKT activation, FOXO4 localizes in the nucleus where it functions as a transcription factor. FOXO4 can also be phosphorylated by JNK following induction of reactive oxygen species (ROS), resulting in transcriptional activation and the induction of a negative feedback mechanism to counteract the ROS. It is through this mechanism that FOXO4 is thought to sensitize cancer cells to doxorubicin-mediated toxicity.Synonyms: Fork head domain transcription factor AFX1, Forkhead box protein O4
    基因ID
    4303
    NCBI登录号
    NP_001164402
    UniProt
    P98177
    途径
    Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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