SPTLC2 抗体 (C-Term)
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Quick Overview for SPTLC2 抗体 (C-Term) (ABIN783536)
抗原
See all SPTLC2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody recognizes Human SPTLC2. At least three isoforms of SPT2 are known to exist, this antibody will not detect isoform b. SPT2 antibody is predicted to not cross-react with SPT1.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS, 0.02 % Sodium Azide
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- SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
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别名
- SPTLC2
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背景
- SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.Synonyms: KIAA0526, LCB 2, LCB2, LCB2a, Long chain base biosynthesis protein 2, SPT 2, SPT2, Serine palmitoyltransferase 2, Serine-palmitoyl-CoA transferase 2
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基因ID
- 9517
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NCBI登录号
- NP_004854
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UniProt
- O15270
抗原
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