CMYA5 抗体 (C-Term)
This anti-CMYA5 antibody is a 兔 多克隆 antibody detecting CMYA5 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for CMYA5 抗体 (C-Term) (ABIN783522)
抗原
CMYA5
(Cardiomyopathy Associated 5 (CMYA5))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This CMYA5 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody detects Myospryn at C-term. SPRYD2 antibody is predicted to not cross-react with other SPRYD protein family members. At least four isoforms of SPRYD2 are known to exist.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat.
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the carboxy terminus of human SPRYD2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- CMYA5 (Cardiomyopathy Associated 5 (CMYA5))
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别名
- Myospryn
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背景
- SPRYD2, also known as Myospryn, was originally identified as the muscle-specific partner of dysbindin and as a Mef-2 target gene. It is a large scaffolding protein localized to the Z-disc/costamere region of striated muscle. SPRYD2 includes a noncanonical tripartite motif (TRIM-like) that lacks the RING domain but consists of a B-box coiled coil (BBC), fibronectin 3 (FN3) repeats, and SPRY domains. SPRYD2 interacts with desmin and calcineurin, and it has been suggested to play a role in the biogenesis of lysosome and negatively regulates slow-fiber-type transformation and skeletal muscle regeneration. SPRYD2 is dysregulated in Duchenne muscular dystrophy.Synonyms: C5orf10, CMYA5, Cardiomyopathy-associated protein 5, DTNBP2, Dystrobrevin-binding protein 2, Genethonin-3, SPRY domain-containing protein 2, SPRYD2, TRIM76, Tripartite motif-containing protein 76
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基因ID
- 202333
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NCBI登录号
- NP_705838
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UniProt
- Q8N3K9
抗原
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