CCDC141 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for CCDC141 抗体 (N-Term) (ABIN783520)
抗原
See all CCDC141 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody detects CCDC141 at N-term.
-
交叉反应 (详细)
- Species reactivity (tested):Human, mouse
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 18 amino acid peptide near the amino terminus of human CCDC141
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
-
-
- CCDC141 (Coiled-Coil Domain Containing 141 (CCDC141))
-
别名
- CCDC141
-
背景
- Coiled-coil domain-containing protein 141 (CCDC141), also known as CAMDI, is a recently identified disrupted in schizophrenia 1 (DISC1)-binding protein that also associates with myosin II. CCDC141 preferentially associates with phosphomyosin II and causes an accumulation of phosphomyosin II at the centrosome in a DISC1-dependent manner. Knockdown of CCDC141 expression by RNAi led to severely impaired radial migration with disoriented chromosomes, suggesting that CCDC141 is required for radial migration through DISC1 and myosin II-mediated centrosome positioning during neuronal development. At least four isoforms of CCDC141 are known to exist.Synonyms: Coiled-coil domain-containing protein 141
-
基因ID
- 285025
-
NCBI登录号
- NP_775919
-
UniProt
- Q6ZP82
抗原
-