AP3B2 抗体 (N-Term)
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Quick Overview for AP3B2 抗体 (N-Term) (ABIN783508)
抗原
See all AP3B2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects AP3 complex subunit beta-2 (N-term).
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- Raised against an 18 amino acid peptide near the amino terminus of human AP3B2
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- AP3B2 (Adaptor-Related Protein Complex 3, beta 2 Subunit (AP3B2))
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别名
- AP3 Complex Subunit beta-2
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背景
- The AP3 complex is a heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. Unlike the homologous AP3B1, AP3B2-containing AP3 complexes are preferentially targeted to neuronal processes, and mice deficient in AP3B2 displayed compromised synaptic zinc stores.Synonyms: AP-3 complex beta-2 subunit, AP3B2, Adapter-related protein complex 3 subunit beta-2, Adaptor protein complex AP-3 beta-2 subunit, Beta 3B Adaptin, Clathrin assembly protein complex 3 beta-2 large chain, Neuron-specific vesicle coat protein beta-NAP, beta-NAP
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基因ID
- 8120
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NCBI登录号
- NP_004635
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UniProt
- Q13367
抗原
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