At least three isoforms of AP3S1 are known to exist, this antibody will detect the two larger isoforms. AP3S1 antibody is predicted to not cross-react with other AP3 protein family members.
交叉反应 (详细)
Species reactivity (tested):Human, mouse, rat
纯化方法
Affinity chromatography purified via peptide column
免疫原
Raised against a 19 amino acid peptide near the center of human AP3S1
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
抗原
AP3S1
(Adaptor-Related Protein Complex 3, sigma 1 Subunit (AP3S1))
别名
AP3 Complex Subunit sigma-1
背景
AP3S1 belongs to the adaptor complexes 3 (AP3) small subunit family which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. AP3 is an heterotetramer composed of two large adaptins (AP3D1, AP3B1 or AP3B2), a medium adaptin (AP3M1 or AP3M2) and a small adaptin (APS1 or AP3S2). AP3S1 Interacts with AGAP1 and may play an important role in carcinoma.Synonyms: AP-3 complex sigma-3A subunit, AP3S1, Adapter-related protein complex 3 sigma-1 subunit, CLAPS3, Clathrin-associated assembly/adapter protein, Sigma 3A Adaptin, Sigma-3A-adaptin, Sigma-adaptin 3a, small 3