KAL1 抗体 (Center)
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Quick Overview for KAL1 抗体 (Center) (ABIN783480)
抗原
See all KAL1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects Anosmin (Center).
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography
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免疫原
- Raised against an 18 amino acid peptide near the center of human Anosmin
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anti-Kallmann Syndrome 1 Sequence (KAL1) (AA 200-300) antibody
KAL1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Kallmann Syndrome 1 Sequence (KAL1) antibodyKAL1 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-Kallmann Syndrome 1 Sequence (KAL1) (AA 548-657) antibodyKAL1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Kallmann Syndrome 1 Sequence (KAL1) (AA 548-657) antibodyKAL1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2E8 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- KAL1 (Kallmann Syndrome 1 Sequence (KAL1))
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别名
- Anosmin-1
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背景
- Mutations in Anosmin-1, an extracellular matrix-associated glycosylated protein, have been linked with Kallmann Syndrome (KS), an X-linked genetic disorder characterized by loss of smell caused by abnormal olfactory bulb development and delayed puberty caused by disrupted migration of the gonadotropin-releasing hormone neuron. Anosmin-1 has been shown to directly bind FGFR1 via its N-terminal cysteine-rich domain, whey-acidic protein-like domain, and its first FnIII repeat with the D2 and D3 ectodomains of FGFR1. It is thought that Anosmin-1 can modulate FGFR1 signaling and have opposing effects on the formation and activation of FGF2-FGFR1-heparing complex.Synonyms: ADMLX, Adhesion molecule-like X-linked, KAL, KAL1, KALIG1, Kallmann syndrome protein
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基因ID
- 3730
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NCBI登录号
- NP_000207
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UniProt
- P23352
抗原
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