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VASH1 抗体 (C-Term)

This anti-VASH1 antibody is a 兔 多克隆 antibody detecting VASH1 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783478
发货至: 中国

Quick Overview for VASH1 抗体 (C-Term) (ABIN783478)

抗原

See all VASH1 抗体
VASH1 (Vasohibin 1 (VASH1))

适用

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人, 小鼠, 大鼠

宿主

  • 39
  • 6

克隆类型

  • 42
  • 3
多克隆

标记

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This VASH1 antibody is un-conjugated

应用范围

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  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detctes Vasohibin-1 / VASH1 at C-term. VASH1 antibody is predicted to not cross-react with other vasohibin protein family members. At least two isoforms are known to exist, this antibody will recognize only the long isoform.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    19 amino acid peptide near the carboxy terminus of human VASH1
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    VASH1 (Vasohibin 1 (VASH1))

    别名

    Vasohibin-1 / VASH1

    背景

    VASH1 was originally identified as an endothelium-derived vascular endothelial growth factor (VEGF)-inducible angiogenesis inhibitor that acts in a negative feedback manner. VASH1 mRNA is expressed brain, heart, kidney and placenta in the adult, with robust expression in various organs during embryonic development. VASH1 expression in tumor cells and tumor vasculature is silenced by methylation by increased expression of Zeste homolog 2 (EZH2). The increase of EZH2 expression is induced by VEGF stimulation, leading to poor clinical prognosis. Recombinant adenovirus expressing VASH prevented tumor angiogenesis and inhibited tumor growth, suggesting that it may be a potentially valuable antitumor therapy in the clinic.Synonyms: KIAA1036, VASH

    基因ID

    22846

    NCBI登录号

    NP_055724

    UniProt

    Q7L8A9
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