MSI2 抗体 (N-Term)
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Quick Overview for MSI2 抗体 (N-Term) (ABIN783472)
抗原
See all MSI2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Musashi-2 at N-term. MSI2 antibody is predicted to not cross-react with MSI1. Multiple isoforms of MSI2 are known to exist.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 15 amino acid peptide near the amino terminus of human MSI2
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anti-Musashi Homolog 2 (MSI2) antibody
MSI2 适用: 人 WB, IHC, IF, IHC (p) 宿主: 小鼠 Monoclonal 2F10 unconjugated
anti-Musashi Homolog 2 (MSI2) antibodyKD Validated MSI2 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB225 unconjugated Recombinant Antibody
anti-Musashi Homolog 2 (MSI2) (N-Term) antibodyMSI2 适用: 人, 小鼠, 大鼠, 斑马鱼, 兔, Cow, 马, Pig, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-328) antibodyMSI2 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D12 unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-328) antibodyMSI2 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Musashi Homolog 2 (MSI2) antibodyMSI2 适用: 人 WB, ELISA, IHC 宿主: 小鼠 Monoclonal 2C11 unconjugated
anti-Musashi Homolog 2 (MSI2) antibodyMSI2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (N-Term) antibodyVerified MSI2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 33-43) antibodyVerified MSI2 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Musashi Homolog 2 (MSI2) (AA 1-328) antibodyMSI2 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- MSI2 (Musashi Homolog 2 (MSI2))
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别名
- Musashi-2
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背景
- Musashi2 (MSI2) is an RNA-binding protein that is highly expressed in precursor cells in the ventricular and subventricular zones of the developing mammalian CNS. Like the related MSI1, MSI2 has been suggested to be involved stem cell production and maintenance. MSI2 is the predominant MSI protein in hematopoietic stem cells, and its knockdown leads to reduced engraftment and depletion in vivo. Expression levels of MSI2 are elevated in myeloid leukemia cells lines, and MSI2 appears to cooperate with BCR-ABL1 to induce an aggressive leukemia, the level of MSI2 directly correlates with decreased survival in patients. MSI2 negatively regulates the asymmetric cell fate determinant NUMB, suggesting that this signaling pathway may provide future targets for future therapies.Synonyms: MSI2, RNA-binding protein Musashi homolog 2
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基因ID
- 124540
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NCBI登录号
- NP_620412
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UniProt
- Q96DH6
抗原
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