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IRF4 抗体 (C-Term)

This anti-IRF4 antibody is a 兔 多克隆 antibody detecting IRF4 in WB 和 EIA. Suitable for 人.
产品编号 ABIN783470
发货至: 中国

Quick Overview for IRF4 抗体 (C-Term) (ABIN783470)

抗原

See all IRF4 抗体
IRF4 (Interferon Regulatory Factor 4 (IRF4))

适用

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宿主

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克隆类型

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多克隆

标记

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This IRF4 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects IRF4 at C-term. IRF4 antibody is predicted to not cross-react with other IRF protein family members. IRF4 often migrates at a higher than predicted molecular weight in SDS-PAGE.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid peptide near the carboxy terminus of human IRF4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    IRF4 (Interferon Regulatory Factor 4 (IRF4))

    别名

    IRF4

    背景

    Interferons (IFNs) are involved in a multitude of immune interactions during viral infections and play a major role in both the induction and regulation of innate and adaptive antiviral mechanisms. During infection, host-virus interactions signal downstream molecules such as transcription factors such as IFN regulatory factor-3 (IRF3) which can act to stimulate transcription of IFN-a/b genes. Another member, IRF7 has been shown to play a role in the transcriptional activation of virus-inducible cellular genes, including interferon beta chain genes. IRF4 expression is tightly regulated in resting primary T cells and plays an essential role in the homeostasis and function of mature lymphocytes. IRF4 is induced by Toll-like receptor (TLR) activation and acts as a negative regulator of TLR signaling.Synonyms: Interferon regulatory factor 4, LSIRF, Lymphocyte-specific interferon regulatory factor, MUM1, Multiple myeloma oncogene 1, NF-EM5

    基因ID

    3662

    NCBI登录号

    NP_001182215

    UniProt

    Q15306

    途径

    Chromatin Binding
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