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- 抗原 See all NUMB 抗体
- NUMB (Numb Homolog (NUMB))
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抗原表位
- C-Term
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适用
- 人, 小鼠, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NUMB antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects NUMB at C-term. At least four isoforms of NUMB are known to exist, this antibody will detect all of them.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 17 amino acid peptide near the carboxy terminus of human NUMB
- Top Product
- Discover our top product NUMB Primary Antibody
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anti-Numb Homolog (NUMB) (C-Term) antibody
Verified NUMB 适用: 人, 小鼠 ELISA, IHC, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 521-640) antibodyNUMB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-135) antibodyNUMB 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4A7-A6 unconjugated
anti-Numb Homolog (NUMB) (AA 1-50) antibodyNUMB 适用: 人, 小鼠, 大鼠, Cow, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (pSer276) antibodyNUMB 适用: 小鼠 WB, ELISA, IF (cc), ICC, IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-135) antibodyNUMB 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (C-Term) antibodyNUMB 适用: 人, 小鼠, 大鼠, 小鸡 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 1-214) antibodyNUMB 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 600-653) antibodyNUMB 适用: 人, 小鼠, 大鼠, 小鸡 WB 宿主: 兔 Polyclonal unconjugated
anti-Numb Homolog (NUMB) (AA 376-482) antibodyNUMB 适用: 人 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- NUMB (Numb Homolog (NUMB))
- 别名
- NUMB (NUMB 产品)
- 别名
- C14orf41 antibody, S171 antibody, c14_5527 antibody, Nb antibody, NUMB, endocytic adaptor protein antibody, numb homolog (Drosophila) antibody, NUMB antibody, Numb antibody, numb antibody
- 背景
- NUMB, the mammalian homolog to the Drosophila asymmetric cell fate determinant NUMB, is thought to share several features molecular mechanisms in mammalian cells, generating asymmetric cell divisions during neurogenesis in vertebrate development as well as in hematopoietic stem cells (1,2). NUMB has been shown to inhibit Notch signaling, and is itself regulated by ubiquitinylation by MDM2. NUMB has also been shown to help activate the tumor suppressor p53, suggesting that loss of NUMB in cancerous cells would not only activate the potential oncogene Notch, but diminish the tumor suppressing effect of p53.Synonyms: Protein S171, Protein numb homolog, h-Numb
- 基因ID
- 8650
- NCBI登录号
- NP_001005743
- UniProt
- P49757
- 途径
- Cell-Cell Junction Organization
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