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2B4 抗体 (C-Term)

This anti-2B4 antibody is a 兔 多克隆 antibody detecting 2B4 in WB 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN783458
发货至: 中国

Quick Overview for 2B4 抗体 (C-Term) (ABIN783458)

抗原

See all 2B4 (CD244) 抗体
2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

适用

人, 小鼠, 大鼠

宿主

  • 58
  • 10
  • 4
  • 4

克隆类型

  • 59
  • 16
  • 1
多克隆

标记

  • 36
  • 4
  • 4
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This 2B4 antibody is un-conjugated

应用范围

  • 62
  • 32
  • 26
  • 26
  • 25
  • 14
  • 9
  • 7
  • 6
  • 5
  • 4
  • 2
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 16
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term

    特异性

    This antibody detects CD244 / SLAMF4 at C-term. At least three isoforms of SLAMF4 are known to exist. The antibody is predicted to not cross-react with other SLAM protein family members.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    16 amino acid peptide near the carboxy terminus of human SLAMF4
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

    别名

    CD244

    背景

    The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4

    基因ID

    51744

    NCBI登录号

    NP_001160135

    UniProt

    Q9BZW8
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