2B4 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for 2B4 抗体 (C-Term) (ABIN783458)
抗原
See all 2B4 (CD244) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects CD244 / SLAMF4 at C-term. At least three isoforms of SLAMF4 are known to exist. The antibody is predicted to not cross-react with other SLAM protein family members.
-
交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Affinity chromatography purified via peptide column
-
免疫原
- 16 amino acid peptide near the carboxy terminus of human SLAMF4
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
-
-
- 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
-
别名
- CD244
-
背景
- The signaling lymphocyte-activation molecule family member 4 (SLAMF4), also known as 2B4, is an important regulator of Natural Killer (NK) cell activation. It is expressed on NK cells as well as on subsets of T cells and interacts with SLAMF2, causing the activation of both SLAMF4- and SLAMF2-expressing cells. Patients with systemic lupus erythmatosus have lower than normal levels of SLAMF4 expressed on their NK cells and monocytes, suggesting that SLAMF4 may play a role in this autoimmune disease.Synonyms: NAIL, NK cell activation-inducing ligand, NK cell type I receptor protein 2B4, NKR2B4, Natural killer cell receptor 2B4
-
基因ID
- 51744
-
NCBI登录号
- NP_001160135
-
UniProt
- Q9BZW8
抗原
-