ZNF281 抗体 (C-Term)
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Quick Overview for ZNF281 抗体 (C-Term) (ABIN783429)
抗原
See all ZNF281 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects ZNF281 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 19 amino acid peptide near the carboxy terminus of human ZFP281
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- ZNF281 (Zinc Finger Protein 281 (ZNF281))
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别名
- ZNF281
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背景
- ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.Synonyms: GC-box-binding zinc finger protein 1, GZP1, ZBP-99, ZBP99, Zinc finger DNA-binding protein 99, Zinc finger protein 281
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基因ID
- 23528
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NCBI登录号
- NP_036614
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UniProt
- Q9Y2X9
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途径
- Embryonic Body Morphogenesis
抗原
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