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ZNF281 抗体 (C-Term)

This anti-ZNF281 antibody is a 兔 多克隆 antibody detecting ZNF281 in WB 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN783429
发货至: 中国

Quick Overview for ZNF281 抗体 (C-Term) (ABIN783429)

抗原

See all ZNF281 抗体
ZNF281 (Zinc Finger Protein 281 (ZNF281))

适用

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  • 1
人, 小鼠

宿主

  • 42
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  • 1

克隆类型

  • 44
  • 3
多克隆

标记

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  • 1
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This ZNF281 antibody is un-conjugated

应用范围

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  • 14
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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 5
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    • 1
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    C-Term

    特异性

    This antibody detects ZNF281 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    19 amino acid peptide near the carboxy terminus of human ZFP281
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    ZNF281 (Zinc Finger Protein 281 (ZNF281))

    别名

    ZNF281

    背景

    ZFP281, also known as ZBP-99, is a member of a conserved family of transcription factors that interact with GC-rich promoters. It contains four Kruppel-like zinc fingers and is highly homologous to ZBP-89, another regulator of ornithine decarboxylase gene expression. ZFP281 also interacts with many other other transcription factors, such as Sp1 to repress vimentin gene transcription. ZFP281 has also been shown to control embryonic stem cell pluripotency by direct regulating specific target genes. ZFP281 phyically interacts with the transcription factos POU5F1, Sox2, and NANOG. Gene expression microarray anlysis indicated that some ZFP281 target genes were activated, while others were repressed upon knockdown of ZFP281 expression, showing that ZFP281 plays bifuctinal roles in regulating gene expression in stem cells.Synonyms: GC-box-binding zinc finger protein 1, GZP1, ZBP-99, ZBP99, Zinc finger DNA-binding protein 99, Zinc finger protein 281

    基因ID

    23528

    NCBI登录号

    NP_036614

    UniProt

    Q9Y2X9

    途径

    Embryonic Body Morphogenesis
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