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ZNF219 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects ZNF219 in WB 和 EIA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN783427
发货至: 中国
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Quick Overview for ZNF219 抗体 (N-Term) (ABIN783427)

抗原

See all ZNF219 抗体
ZNF219 (Zinc Finger Protein 219 (ZNF219))

适用

  • 10
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 10

克隆类型

  • 10
多克隆

标记

  • 10
This ZNF219 antibody is un-conjugated

应用范围

  • 10
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody detects ZNF219 at N-term. At least two isoforms of ZFP219 are known to exist, this antibody will recognize both.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography purified via peptide column

    免疫原

    18 amino acid peptide near the amino terminus of human ZFP219
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • 抗原

    ZNF219 (Zinc Finger Protein 219 (ZNF219))

    别名

    ZNF219

    背景

    ZFP219 is a developmentally regulated member of the Kruppel-like zinc finger gene family that is thought to function as a transcriptional repressor. Yeast two-hybrid screening showed association with Sox9, a transcription factor that is essential for chondrogenesis. ZFP219 is specifically expressed in the developing limb buds and colocalizes with Sox9 in the nucleus. Knockdown of ZFP219 expression decreased Sox9-induced mRNA expression, and a dominant-negative mutant of ZFP219 inhibited Bmp2-induced chondrocyte differentiation, suggesting that ZFP219 plays an important role as a transcriptional partner of Sox9 in the regulation of chondrocyte differentiation.Synonyms: Zinc finger protein 219

    基因ID

    51222

    NCBI登录号

    NP_001095142

    UniProt

    Q9P2Y4
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