TM4SF1 抗体 (N-Term)
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Quick Overview for TM4SF1 抗体 (N-Term) (ABIN783425)
抗原
See all TM4SF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects TM4SF1 at N-term. At least three isoforms of TM4SF1 are known to exist, this antibody will recognize only the two largest isoforms. TM4SF1 antibody is predicted to not cross-react with other tetraspanin proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the amino terminus of human TM4SF1
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anti-Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 115-161) antibody
TM4SF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 16-45), (N-Term) antibodyTM4SF1 适用: 人, 小鼠 IHC (p), WB 宿主: 兔 Polyclonal RB32161 unconjugated
anti-Transmembrane 4 L Six Family Member 1 (TM4SF1) (AA 110-202) antibodyTM4SF1 适用: 人 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- TM4SF1 (Transmembrane 4 L Six Family Member 1 (TM4SF1))
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别名
- TM4SF1
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背景
- TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.Synonyms: M3S1, Membrane component surface marker 1, TAAL6, Transmembrane 4 L6 family member 1, Tumor-associated antigen L6
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基因ID
- 4071
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NCBI登录号
- NP_055035
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UniProt
- P30408
抗原
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