ESRP1 抗体 (N-Term)
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Quick Overview for ESRP1 抗体 (N-Term) (ABIN783405)
抗原
See all ESRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects ESRP1 / RBM35A at N-term. It is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist, this antibody will detect all five.
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交叉反应 (详细)
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- Affinity Chromatography purified via peptide column
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免疫原
- 12 amino acid peptide near the amino terminus of Human RBM35A
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))
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别名
- ESRP1 / RBM35A
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背景
- RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.Synonyms: Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A
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基因ID
- 54845
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NCBI登录号
- NP_001030087
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UniProt
- Q6NXG1
抗原
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