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ESRP1 抗体 (N-Term)

This 兔 多克隆 anti-ESRP1 antibody specifically detects ESRP1 in WB, IHC (p), IF 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN783405
发货至: 中国
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Quick Overview for ESRP1 抗体 (N-Term) (ABIN783405)

抗原

See all ESRP1 抗体
ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

适用

  • 17
  • 5
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  • 2
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人, 小鼠, 大鼠

宿主

  • 15
  • 4

克隆类型

  • 17
  • 2
多克隆

标记

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This ESRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 8
    • 3
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    • 1
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    N-Term

    特异性

    This antibody detects ESRP1 / RBM35A at N-term. It is predicted to not cross-react with other RBM35/ESRP family members. At least five isoforms of RBM35A are known to exist, this antibody will detect all five.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Affinity Chromatography purified via peptide column

    免疫原

    12 amino acid peptide near the amino terminus of Human RBM35A
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    ESRP1 (Epithelial Splicing Regulatory Protein 1 (ESRP1))

    别名

    ESRP1 / RBM35A

    背景

    RBM35A, also known as ESRP1, is a mRNA splicing factor that with its related protein RBM35B (ESRP2) are coordinators of an epithelial cell-type-specific splicing program. RBM35A contains three putative RNA recognition motifs and acts by directly binding specific sequences in mRNAs. RBM35A is involved in posttranscriptional regulation of a number of genes such as FGFR2, CD44, CTNND1, and ENAH by exerting a differential effect on protein translation via 5' UTRs of mRNAs. Other recent studies have shown that RMB35A may also act as a novel tumor suppressor.Synonyms: Epithelial splicing regulatory protein 1, RNA-binding motif protein 35A, RNA-binding protein 35A

    基因ID

    54845

    NCBI登录号

    NP_001030087

    UniProt

    Q6NXG1
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