HMMR 抗体 (N-Term)
(1 reference)Quick Overview for HMMR 抗体 (N-Term) (ABIN783397)
抗原
See all HMMR 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects CD168 / HMMR at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 18 amino acid peptide near the amino terminus of human RHAMM
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anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 341-440) antibody
HMMR 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 306-497) antibodyHMMR 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 2F2C9 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 51-150) antibodyHMMR 适用: 人, 小鼠 WB, ELISA, FACS, IHC (p), ICC, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 280-340) antibodyHMMR 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 577-724) antibodyHMMR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) antibodyHMMR 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 1-300) antibodyHMMR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 668-697), (C-Term) antibodyHMMR 适用: 人, 小鼠 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB17647 unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 478-653) antibodyHMMR 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR) (AA 706-724), (C-Term) antibodyHMMR 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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: "Targeting Long Noncoding RNA HMMR-AS1 Suppresses and Radiosensitizes Glioblastoma." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 5, pp. 456-466, (2018) (PubMed).
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: "Targeting Long Noncoding RNA HMMR-AS1 Suppresses and Radiosensitizes Glioblastoma." in: Neoplasia (New York, N.Y.), Vol. 20, Issue 5, pp. 456-466, (2018) (PubMed).
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- HMMR (Hyaluronan-Mediated Motility Receptor (RHAMM) (HMMR))
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别名
- CD168 / HMMR
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背景
- The hyaluronan-mediated motility receptor, also known as RHAMM, was initially identified as a soluble protein that could be released by sub-confluent migrating cells, promoting cell motility and invasion via interactions with hyaluronan (HA) and the cell surface. While RHAMM is normally poorly expressed in most normal tissues and is not required for embryonic development or normal cell homeostasis functions, its expression is increased during wound repair in response to hypoxia and fibrogenic factors. However, its overexpression is transforming in multiple types of cancers and is required for maintaining RAS transformation. RHAMM associates with BRCA1 and BARD1, attenuating the mitotic-spindle-promoting activity of RHAMM, which may contribute to tumor progression by promoting genomic instability.Synonyms: Hyaluronan mediated motility receptor, IHABP, Intracellular hyaluronic acid-binding protein, RHAMM, Receptor for hyaluronan-mediated motility
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基因ID
- 3161
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NCBI登录号
- NP_001136028
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UniProt
- O75330
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途径
- Glycosaminoglycan Metabolic Process
抗原
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