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- 抗原 See all LRRTM2 抗体
- LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))
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抗原表位
- C-Term
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适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LRRTM2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Enzyme Immunoassay (EIA)
- 特异性
- This antibody detects LRRTM2 at C-term. LRRTM2 antibody is predicted to not cross-react with other LRRTM family members.
- 交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- 17 amino acid peptide near the carboxy terminus of human LRRTM2
- Top Product
- Discover our top product LRRTM2 Primary Antibody
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- 抗原
- LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2 (LRRTM2))
- 别名
- LRRTM2 (LRRTM2 产品)
- 别名
- sc:d0320 antibody, AI851755 antibody, BB129880 antibody, C630011A14Rik antibody, mKIAA0416 antibody, leucine rich repeat transmembrane neuronal 2 antibody, LRRTM2 antibody, lrrtm2 antibody, Lrrtm2 antibody
- 背景
- The Leucine-rich repeat transmembrane neuronal proteins (LRRTMs) are differentially expressed in the nervous system and were recently found to instruct presynaptic and mediate postsynaptic glutamatergic differentiation, with LRRTM1 and LRRTM2 most potent at inducing presynaptic differentiation. Each LRRTM protein is a type I transmembrane containing ten extracellular leucine-rich repeats and a short intracellular tail and has a developmentally regulated pattern distinct from all others. LRRTM2 interacts with PSD-95 and regulates the surface expression of AMPA receptors. LRRTM2 also functions as a neurexin ligand, binding both Neurexin 1-alpha and -beta, suggesting that LRRTM2-Neurexin1 interaction plays a critical role in regulatory excitatory synapse development.Synonyms: KIAA0416, LRRN2, Leucine-rich repeat neuronal 2 protein, Leucine-rich repeat transmembrane neuronal protein 2
- 基因ID
- 26045
- NCBI登录号
- NP_056379
- UniProt
- O43300
- 途径
- Synaptic Membrane
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