AXIN2 抗体 (C-Term)
Quick Overview for AXIN2 抗体 (C-Term) (ABIN783373)
抗原
See all AXIN2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- Thias antibody detects Axin-2 at C-term. It is predicted to not cross-react with AXIN2. At least four isoforms of AXIN2 are known to exist, this antibody will recognize all four.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 20 amino acid peptide near the carboxy terminus of human AXIN2
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anti-Axin 2 (AXIN2) (AA 650-750) antibody
AXIN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843) antibodyAXIN2 适用: 人 WB, IHC, ELISA, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 56-73) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, FACS 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 331-430) antibodyAXIN2 适用: 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 350-631) antibodyAXIN2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 11-77) antibodyAXIN2 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 611-710) antibodyAXIN2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3B6 unconjugated
anti-Axin 2 (AXIN2) (N-Term) antibodyAXIN2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Axin 2 (AXIN2) (AA 816-843), (C-Term) antibodyAXIN2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB26798 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- AXIN2 (Axin 2 (AXIN2))
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别名
- Axin-2
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背景
- Like the related protein AXIN1, AXIN2 is thought to play an important role in the regulation of the stability of beta-catenin in the Wnt signaling pathway. In mouse, AXIN2 organizes a multiprotein complex of APC (adenomatous polyposis of the colon), beta-catenin, glycogen synthase kinase 3-beta, and AXIN2, which leads to the degradation of beta-catenin, which is thought to be an important event in the genesis of a number of malignancies. The AXIN2 gene has been mapped to 17q23-q24, a region that shows frequent loss of heterozygosity in breast cancer, neuroblastoma, and other tumors. Mutations in this gene have been associated with colorectal cancer with defective mismatch repair.Synonyms: AXIN2, Axin-like protein, Axis inhibition protein 2, Conductin
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基因ID
- 8313
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NCBI登录号
- NP_004646
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UniProt
- Q9Y2T1
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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