This antibody detects ZMYM3 at N-term. At least three isoforms of ZMYM3 are known to exist, this antibody will detect all three. ZMYM3 antibody is predicted to not cross-react with other ZMYM protein family members.
交叉反应 (详细)
Species reactivity (tested):Human, mouse
纯化方法
Affinity chromatography purified via peptide column
免疫原
20 amino acid peptide near the amino terminus of human AXIN2
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
抗原
ZMYM3
(Zinc Finger Protein 261 (ZMYM3))
别名
ZMYM3
背景
Zinc-finger proteins contain DNA-binding domains characterized by the unique role of zinc and have a wide variety of functions such as transcriptional activation or repression. The protein folding and the DNA binding ability are governed by the coordination of a zinc ion. As a member of the MYM (myeloproliferative and mental retardation) gene family, ZMYM3 is highly conserved in vertebrates and most abundantly expressed in the brain. The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent. A chromosomal translocation (X,13) involving this gene is associated with X-linked mental retardation.Synonyms: DXS6673E, KIAA0385, ZNF261, Zinc finger MYM-type protein 3, Zinc finger protein 261