ZBTB5 抗体 (C-Term)
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Quick Overview for ZBTB5 抗体 (C-Term) (ABIN783357)
抗原
See all ZBTB5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects ZBTB5 at C-term. At least two isoforms of ZBTB5 are known to exist, this antibody will recognize both isoforms. This antibody is predicted to not cross-react with other ZBTB protein family members.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid peptide near the carboxy terminus of human ZBTB6
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anti-Zinc Finger and BTB Domain Containing 5 (ZBTB5) (AA 581-677) antibody
ZBTB5 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger and BTB Domain Containing 5 (ZBTB5) (AA 178-206), (N-Term) antibodyZBTB5 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB26523 unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- ZBTB5 (Zinc Finger and BTB Domain Containing 5 (ZBTB5))
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别名
- ZBTB5
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背景
- The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. ZBTB5 was identified though sequence analysis as a POZ domain Kruppel-like zinc finger (POK) protein. Further experiments indicated that it binds DNA and can directly repress transcription of the cell cycle arrest gene p21. ZBTB5 can also interact with co-repressor histone deacetylase complexes such as BCoR, NCoR, and SMRT via its POZ domain, resulting in deacetylation of histones Ac-H3 and Ac-H4 at the proximal promoter. ZBTB5 stimulates both cell proliferation and cell cycle progression, suggesting that it may act as a potential proto-oncogene.Synonyms: KIAA0354, Zinc finger and BTB domain-containing protein 5
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基因ID
- 9925
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NCBI登录号
- NP_055687
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UniProt
- O15062
抗原
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