This antibody detects ZBTB3 at C-term. At least three isoforms of ZBTB3 are known to exist. This antibody is predicted to not cross-react with other ZBTB protein family members.
交叉反应 (详细)
Species reactivity (tested):Human, mouse, rat
纯化方法
Affinity chromatography purified via peptide column
免疫原
17 amino acid peptide near the carboxy terminus of human ZBTB3
ZBTB3
适用: 人
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy3
应用备注
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
缓冲液
PBS containing 0.02 % sodium azide
储存液
Sodium azide
注意事项
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
注意事项
Avoid repeated freezing and thawing.
储存条件
4 °C/-20 °C
储存方法
Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
抗原
ZBTB3
(Zinc Finger and BTB Domain Containing 3 (ZBTB3))
别名
ZBTB3
背景
The ZBTB family of proteins is comprised of diverse zinc finger proteins that also contain a BTB (BR-C, ttk and bab) domain. While little is known about ZBTB3, the related protein ZBTB2 is thought to be phosphorylated in response to the DNA damage, probably by either ATM or ATR. Other ZBTB proteins, such as ZBTB4 and ZBTB38 bind methylated DNA and repress transcription, suggesting that ZBTB3 may also act as a transcription repressor.Synonyms: Zinc finger and BTB domain-containing protein 3