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Aggrecan 抗体 (N-Term)

ACAN 适用: 人 IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN782461
发货至: 中国
  • 抗原 See all Aggrecan (ACAN) 抗体
    Aggrecan (ACAN)
    抗原表位
    • 15
    • 15
    • 6
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 65
    • 53
    • 40
    • 31
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 78
    • 18
    • 1
    克隆类型
    • 71
    • 26
    多克隆
    标记
    • 45
    • 15
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This Aggrecan antibody is un-conjugated
    应用范围
    • 70
    • 39
    • 26
    • 26
    • 25
    • 20
    • 14
    • 12
    • 8
    • 8
    • 4
    • 4
    • 3
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应 (详细)
    Species reactivity (tested):Human.
    免疫原
    Synthetic peptide (- KLH conjugated) corresponding to N-terminal domain of Human Aggrecan.
    亚型
    IgG
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  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.09 % Sodium Azide as preservative.
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原
    Aggrecan (ACAN)
    别名
    Aggrecan (ACAN 产品)
    别名
    AGC1 antibody, AGCAN antibody, CSPG1 antibody, CSPGCP antibody, MSK16 antibody, SEDK antibody, Agc antibody, Agc1 antibody, Cspg1 antibody, b2b183Clo antibody, cmd antibody, aggrecan antibody, aggrecan core protein antibody, ACAN antibody, Acan antibody, LOC100380783 antibody, AGC antibody
    背景
    Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.Synonyms: ACAN, AGC1, CSPG1, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1, MSK16
    基因ID
    9606
    UniProt
    P16112
    途径
    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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