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Aggrecan 抗体 (N-Term)

This 兔 多克隆 antibody specifically detects Aggrecan in IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN782461
发货至: 中国
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Quick Overview for Aggrecan 抗体 (N-Term) (ABIN782461)

抗原

See all Aggrecan (ACAN) 抗体
Aggrecan (ACAN)

适用

  • 93
  • 45
  • 32
  • 16
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1

宿主

  • 90
  • 20
  • 1

克隆类型

  • 73
  • 38
多克隆

标记

  • 52
  • 15
  • 6
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Aggrecan antibody is un-conjugated

应用范围

  • 72
  • 50
  • 25
  • 23
  • 15
  • 15
  • 14
  • 13
  • 8
  • 7
  • 5
  • 5
  • 3
  • 1
  • 1
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 15
    • 7
    • 6
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human.

    免疫原

    Synthetic peptide (- KLH conjugated) corresponding to N-terminal domain of Human Aggrecan.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.
  • 抗原

    Aggrecan (ACAN)

    别名

    Aggrecan

    背景

    Aggrecan is a member of a family of large, aggregating proteoglycans (also including versican, brevican and neurocan) which is found in articular cartilage. Aggrecan is composed of three major domains: G1, G2, and G3. Between the G1 and G2 domains there is an interglobulin region (IGD). The IGD region is the major site of cleavage by specific proteases like metalloproteinases (MMPs) and aggrecanase. Aggrecan cleavage has been associated with a number of degenerative diseases including rheumatoid arthritis and osteoarthritis. There is evidence that this family of proteoglycans modulates cell adhesion, migration, and axonal outgrowth in the CNS.Synonyms: ACAN, AGC1, CSPG1, Cartilage-specific proteoglycan core protein, Chondroitin sulfate proteoglycan core protein 1, MSK16

    基因ID

    9606

    UniProt

    P16112

    途径

    Glycosaminoglycan Metabolic Process, Dicarboxylic Acid Transport
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