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- 抗原 See all Synaptojanin 1 (SYNJ1) 抗体
- Synaptojanin 1 (SYNJ1)
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抗原表位
- C-Term
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适用
- 大鼠
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This Synaptojanin 1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 特异性
- Specific for the ~145k Synaptojanin I protein in Western blots of Rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody. Does not cross react with Mouse.
- 交叉反应 （详细）
- Species reactivity (tested):Rat.
- 纯化方法
- Protein G Chromatography of Culture Supernatant.
- 免疫原
- Recombinant protein corresponding to amino acid residues from the C-terminal region of Rat Synaptojanin 1.
- 克隆位点
- 5H1
- 亚型
- IgG
- Top Product
- Discover our top product SYNJ1 Primary Antibody
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anti-Synaptojanin 1 (SYNJ1) (AA 1030-1261) antibody
SYNJ1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (N-Term) antibodySYNJ1 适用: 人, 大鼠, 小鼠, Pig, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1474-1573) antibodySYNJ1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A2 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 481-580) antibodySYNJ1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1517-1551), (C-Term) antibodySYNJ1 适用: 人 WB 宿主: 兔 Polyclonal RB52973 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1148-1182), (C-Term) antibodySYNJ1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB53251 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1474-1573) antibodySYNJ1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (C-Term) antibodySYNJ1 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal 5H1 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1190-1239) antibodySYNJ1 适用: 人, Pig, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 147-196) antibodySYNJ1 适用: 人, Pig, 马, 兔, Cow, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- -20 °C
- 储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- 抗原
- Synaptojanin 1 (SYNJ1)
- 别名
- Synaptojanin-1 / SYNJ1 (SYNJ1 产品)
- 别名
- CG6562 antibody, Dmel\\CG6562 antibody, IPP antibody, Synj antibody, fb02f11 antibody, fi15a11 antibody, nrc antibody, wu:fb02f11 antibody, wu:fi15a11 antibody, SYNJ1 antibody, INPP5G antibody, A930006D20Rik antibody, AA675315 antibody, mKIAA0910 antibody, Synaptojanin antibody, synaptojanin 1 antibody, Synj antibody, synj1 antibody, SYNJ1 antibody, Synj1 antibody
- 背景
- Synaptojanin is a phosphatidylinositol phosphatase involved in clathrinmediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms, one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues (Ramjaun AR & McPherson PS, 1996). The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down's syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidyl-inositol-4,5-bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice (Voronov SV et al., 2008).Synonyms: 4, 5-trisphosphate 5-phosphatase 1, INPP5G, KIAA0910, Synaptic Marker, Synaptic inositol-1
- 基因ID
- 85238
- NCBI登录号
- NP_445928
- UniProt
- Q62910
- 途径
- Inositol Metabolic Process, Synaptic Vesicle Exocytosis
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