Synaptojanin 1 抗体 (C-Term)
Quick Overview for Synaptojanin 1 抗体 (C-Term) (ABIN782444)
抗原
See all Synaptojanin 1 (SYNJ1) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- C-Term
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特异性
- Specific for the ~145k Synaptojanin I protein in Western blots of Rat brain extracts. Immunolabeling blocked by preadsorption of antibody with the protein used to generate the antibody. Does not cross react with Mouse.
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交叉反应 （详细）
- Species reactivity (tested):Rat.
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纯化方法
- Protein G Chromatography of Culture Supernatant.
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免疫原
- Recombinant protein corresponding to amino acid residues from the C-terminal region of Rat Synaptojanin 1.
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亚型
- IgG
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anti-Synaptojanin 1 (SYNJ1) (AA 1030-1261) antibody
SYNJ1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (N-Term) antibodySYNJ1 适用: 人, 大鼠, 小鼠, Pig, 犬, 豚鼠, 马, 兔, Cow WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1474-1573) antibodySYNJ1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A2 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 481-580) antibodySYNJ1 适用: 大鼠 ELISA, IF (cc), IF (p), IHC (fro), ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1148-1182), (C-Term) antibodySYNJ1 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal RB53251 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1517-1551), (C-Term) antibodySYNJ1 适用: 人 WB 宿主: 兔 Polyclonal RB52973 unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1474-1573) antibodySYNJ1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 1190-1239) antibodySYNJ1 适用: 人, Pig, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) (AA 147-196) antibodySYNJ1 适用: 人, Pig, 马, 兔, Cow, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Synaptojanin 1 (SYNJ1) antibodySYNJ1 适用: 大鼠 WB, IHC 宿主: 小鼠 Monoclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- Synaptojanin 1 (SYNJ1)
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别名
- Synaptojanin-1 / SYNJ1
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背景
- Synaptojanin is a phosphatidylinositol phosphatase involved in clathrinmediated endocytosis of synaptic vesicles. Synaptojanin 1 has two alternatively spliced isoforms, one that is ~ 145 kDA and is exclusively expressed in neurons, and the other ~ 170 kDa which is expressed in non-neuronal, peripheral tissues (Ramjaun AR & McPherson PS, 1996). The gene which encodes Synaptojanin 1, SYNJ1, has been mapped to chromosome 21 thus making it a candidate for involvement in Down's syndrome (DS). It has recently been demonstrated that Ts65Dn mice (the most commonly used model of DS) have altered phosphatidyl-inositol-4,5-bisphosphate metabolism. This defect is rescued by restoring SYNJ1 to disomy in the Ts65Dn mice (Voronov SV et al., 2008).Synonyms: 4, 5-trisphosphate 5-phosphatase 1, INPP5G, KIAA0910, Synaptic Marker, Synaptic inositol-1
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基因ID
- 85238
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NCBI登录号
- NP_445928
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UniProt
- Q62910
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途径
- Inositol Metabolic Process, Synaptic Vesicle Exocytosis
抗原
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