VAMP1 抗体
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北京 101111
Quick Overview for VAMP1 抗体 (ABIN782443)
抗原
See all VAMP1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- The antibody is specific for the ~16 kDa synaptobrevin protein in Western blots of rat brain lysate.
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交叉反应 (详细)
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Species reactivity (tested):Human, Pig, Hamster, Rat, Rabbit, Mouse, and Bovine.
Also reacts to: VAMP2 -
纯化方法
- Affinity Chromatography.
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免疫原
- Synaptic immunoprecipitate (crude) from Human brain.
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亚型
- IgM
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody undiluted (in aliquots) at -20 °C.
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- VAMP1 (Vesicle-Associated Membrane Protein 1 (Synaptobrevin 1) (VAMP1))
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别名
- VAMP-1 / Synaptobrevin-1
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背景
- Synaptobrevin (aka VAMP) is an integral membrane protein of synaptic vesicles that plays a major role in the formation of larger SNARE complexes, along with SNAP-25 and syntaxin. Synaptobrevin has been shown to be essential for two fast synapse-specific membrane trafficking processes: fast exocytosis for neurotransmitter release and fast endocytosis that mediates rapid recycling of synaptic vesicles (Deak et al., 2004). Decreased levels of synaptobrevin in human hippocampus and cortex have been correlated with cognitive defects in Alzheimer's disease (Sze et al., 2000).Synonyms: SYB1, VAMP1, Vesicle-associated membrane protein 1
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基因ID
- 6843
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NCBI登录号
- NP_055046
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UniProt
- P23763
抗原
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