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FTO 抗体 (N-Term)

This 小鼠 单克隆 antibody specifically detects FTO in WB, IF 和 IHC (p). It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马 和 Non-Human Primate.
产品编号 ABIN782440
发货至: 中国
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Quick Overview for FTO 抗体 (N-Term) (ABIN782440)

抗原

See all FTO 抗体
FTO (Fat Mass and Obesity-Associated (FTO))

适用

  • 84
  • 28
  • 28
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠, 犬, Cow, 绵羊, 马, Non-Human Primate

宿主

  • 79
  • 9
  • 1
  • 1
小鼠

克隆类型

  • 47
  • 43
单克隆

标记

  • 42
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This FTO antibody is un-conjugated

应用范围

  • 77
  • 35
  • 22
  • 19
  • 16
  • 14
  • 14
  • 12
  • 9
  • 6
  • 3
  • 2
  • 1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

5-2H10
  • 抗原表位

    • 15
    • 13
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    Specific for the ~58 kDa Fto protein in Western blots of rat testes lysate. The antibody has also been used for Immunocytochemistry with neuronal progenitor cells.

    交叉反应 (详细)

    Species reactivity (expected):Bovine, Canine, Horse, non-Human Primate and Sheep.
    Species reactivity (tested):Human, Mouse, Rat.

    纯化方法

    Protein G Chromatography of Culture Supernatant

    免疫原

    Synthetic peptide -KLH conjugated corresponding to amino acid residues from the N- terminal region of FTO

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    FTO (Fat Mass and Obesity-Associated (FTO))

    别名

    FTO

    背景

    The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that Fto is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009).Synonyms: Fat mass and obesity-associated protein, KIAA1752

    基因ID

    79068

    NCBI登录号

    NP_001073901

    UniProt

    Q9C0B1
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