FTO 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for FTO 抗体 (N-Term) (ABIN782440)
抗原
See all FTO 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- N-Term
-
特异性
- Specific for the ~58 kDa Fto protein in Western blots of rat testes lysate. The antibody has also been used for Immunocytochemistry with neuronal progenitor cells.
-
交叉反应 (详细)
-
Species reactivity (expected):Bovine, Canine, Horse, non-Human Primate and Sheep.
Species reactivity (tested):Human, Mouse, Rat. -
纯化方法
- Protein G Chromatography of Culture Supernatant
-
免疫原
- Synthetic peptide -KLH conjugated corresponding to amino acid residues from the N- terminal region of FTO
-
亚型
- IgG
-
-
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- 10 mM HEPES ( pH 7.5), 150 mM NaCl, 100 μg/mL BSA and 50 % Glycerol
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- FTO (Fat Mass and Obesity-Associated (FTO))
-
别名
- FTO
-
背景
- The FTO gene is the most robust gene for common obesity characterized to date. FTO gene expression has been found to be significantly upregulated in the hypothalamus of rats after food deprivation and strongly negatively correlated with the expression of orexin peptide which is involved in the stimulation of food intake (Fredricksson R et al., 2008). Deletion analysis of FTO gene in mice showed that Fto is functionally involved in the control of both energy intake and energy expenditure (Fischer J et al., 2009).Synonyms: Fat mass and obesity-associated protein, KIAA1752
-
基因ID
- 79068
-
NCBI登录号
- NP_001073901
-
UniProt
- Q9C0B1
抗原
-